Was the last year under the RS4 125 name and the last before Euro 4.
| MODEL | APRILIA RS4 125 2016 |
| Year | 2016 |
| Engine Type | Four-stroke, single cylinder, DOHC, 4 valves |
| Displacement / Capacity | 124.8 cc / 7.6 cu in |
| Bore X Stroke | 58 x 47 mm / 2.3 x 1.9 in |
| Compression Ratio | 12.5:1 |
| Cooling System | Liquid cooled |
| Max Power | 11.7 kW / 16 hp @ 10500 rpm |
| Max Torque | 11 Nm / 8.1 lb-ft @ 8500 rpm |
| Ignition | Electronic, CDI |
| Induction | Electronic fuel injection, Magneti Marelli MIU G3, 32 mm throttle body |
| Start System | Electric |
| TRANSMISSION SPECS | |
| Lubrication | Wet sump |
| Gear Box | 6-speed |
| Clutch | Wet multi-plate (oil bath) |
| Final Drive | Chain |
| CHASSIS SPECS | |
| Frame | Aluminium perimeter frame with die-cast spars |
| Front Suspension | 41 mm upside-down fork, 110 mm / 4.3 in travel |
| Rear Suspension | Asymmetric swingarm with monoshock, 130 mm / 5.1 in travel |
| Front Brakes | Single 300 mm stainless steel disc, radial 4-piston caliper |
| Rear Brakes | Single 218 mm stainless steel disc, single-piston caliper |
| DIMENSION SPECS | |
| Overall Length | 1953 mm / 76.9 in |
| Overall Width | 740 mm / 29.1 in |
| Overall Height | 1138 mm / 44.8 in |
| Seat Height | 820 mm / 32.3 in |
| Wheelbase | 1350 mm / 53.1 in |
| Ground Clearance | — |
| Dry Weight | 120 kg / 265 lbs |
| Wet Weight | — |
| WHEEL SPECS | |
| Front Tyre | 110/80-17 |
| Rear Tyre | 130/70-17 |
| FUEL SYSTEM | |
| Fuel Capacity | 14.5 Litres / 3.8 US gal |
| Fuel Consumption | — |
| Top Speed | 110 km/h / 68 mph |
2016 was the last year under the RS4 125 name and the last before Euro 4. The bike was mechanically the same as the 2011 original, with the fuel-injected four-valve single, aluminium perimeter frame and radial front brake, and it still had no ABS. Its successor, revealed at the end of 2016, added Euro 4 compliance and front ABS and went back to the RS 125 name.
